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Brain Complexity Directly Mapped Digitally
There are also numerous anatomical data.
Wiring Diagrams of Brain Regions
Humans are much more complex (over ten billion neurons), but for this there are only five
classes of component neurons here. For the rat hippocampus, there is detailed information
and circuit diagrams on the net:
Neuroactivity Detection
In order to see individual nerve cells in their activity, i.e. to pay attention to them, we have
developed a tool ourselves: The “activity detection tool” uses a Fourier transform. A nice
introduction to such approaches is a paper that works in particular with segmentation and
ImageJ (Schulze et al. 2013):
15.4
Possible Objectives
What should be the next step? Well, bioinformatics is very good at analysing sequences,
identifying domains and thus elucidating functions of proteins in the nervous system very
well. Receptors can also be modelled in terms of their structure and their detailed dynam
ics and function can be investigated in detail. Finally, larger network analyses, in particular
on the “connectome”, the connection of nerve cells, are already planned for several organ
isms and their nervous systems (mouse, human, insects and others) or have already been
completely carried out in first drafts (cordworm C. elegans, molluscs). Therefore, it is safe
to say that bioinformatics is doing good work in the areas of understanding neurobiol
ogy and basic research.
The same applies to medical causal research, although here the impetus from bioinfor
matics is particularly concerned with uncovering the molecular causes of diseases,
thereby supporting diagnosis or even predicting innovative therapies.
More ethically and technically challenging is work on artificial intelligence or on con
sciousness. Here, it is an ethical imperative to leave all central, moral or ethical decisions
to humans, to take this into account already when structuring the problem and the decision
The Sausage Atlas
https://www.wormatlas.org/neuronalwiring.html
https://www.temporal-lobe.com/background/connectome
https://www.ncbi.nlm.nih.gov/pubmed/23537512
15 How Is Our Own Extremely Powerful Brain Constructed?